Panama Canal Cruises

Sail Central America from Atlantic to Pacific

View natural beauty and an engineering marvel across the Panama Canal

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Recommended Panama Canal Cruises

Featured Panama Canal Cruises

Experience the trip of a lifetime as you navigate the 50-mile Panama Canal onboard a cheap Panama Canal cruise, including one of these highly-rated Panama Canal cruises:
  • Emerald Princess
    4 rating out of 5  (1,211 reviews)

    12 Night Panama Canal with Costa Rica & Caribbean

    Emerald Princess

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Oranjestad, Aruba
    • Willemstad, Curacao
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • George Town, Grand Cayman
    Sailing Dates:
    • March 2025
    interior from
    $1,248
    $104pernight
    oceanview from
    $1,473
    $123pernight
    balcony from
    $2,686
    $224pernight
    suite from
    $4,239
    $353pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards: Earn more perks on this cruise! Click for details
    • Drop & Go Sale: Limited Time Reduced Rates!
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • End of Year Sale: Save Up to 40% + Up to $200 In Savings & More
     
    Interior from $1,248
    ($104pernight)
    4 rating out of 5  (1,211 reviews)
  • Carnival Miracle
    4 rating out of 5  (2,764 reviews)

    8 Night Panama Canal

    Carnival Miracle

    Departing from: Tampa, Florida
    Ports of Call:
    • Puerto Limon, Costa Rica
    • Colon, Panama
    • George Town, Grand Cayman
    Sailing Dates:
    • January 2026
    • March 2026
    interior from
    $1,074
    $134pernight
    oceanview from
    $1,224
    $153pernight
    balcony from
    $1,484
    $186pernight
    suite from
    Call for availability
    Rewards & Bonus Offers:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Cruises.com Rewards: Earn more perks on this cruise! Click for details
    • VIFP Members: Unlock big savings!
    • Early Saver Sale: 40% Savings & Up to $50 to Spend Onboard
    • Exclusive: Up to $75 to Spend on Board
     
    Interior from $1,074
    ($134pernight)
    4 rating out of 5  (2,764 reviews)
  • Carnival Spirit
    4 rating out of 5  (985 reviews)

    16 Night Panama Canal Carnival Journeys - Eastbound

    Carnival Spirit

    Departing from: Seattle, Washington
    Ports of Call:
    • Cabo San Lucas, Mexico
    • Puntarenas, Costa Rica
    • Panama Canal Full Transit
    • Cartagena, Colombia
    • New Orleans, Louisiana
    Sailing Dates:
    • October 2025
    interior from
    $1,113
    $70pernight
    oceanview from
    $1,433
    $90pernight
    balcony from
    $1,703
    $106pernight
    suite from
    Call for availability
    Rewards & Bonus Offers:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Cruises.com Rewards: Earn more perks on this cruise! Click for details
    • VIFP Members: Unlock big savings!
    • Early Saver Sale: 40% Savings & Up to $50 to Spend Onboard
    • Exclusive: Up to $75 to Spend on Board
     
    Interior from $1,113
    ($70pernight)
    4 rating out of 5  (985 reviews)
  • Norwegian Gem
    3.8 rating out of 5  (2,498 reviews)

    11 Night Panama Canal: Mexico Costa Rica & Belize

    Norwegian Gem - OPEN BAR!

    Departing from: Miami, Florida
    Ports of Call:
    • George Town, Grand Cayman
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • Harvest Caye, Belize
    • Cozumel, Mexico
    Sailing Dates:
    • January 2025
    interior from
    Call for availability
    oceanview from
    Call for availability
    balcony from
    Call for availability
    suite from
    $5,141
    $467pernight
    Rewards & Bonus Offers:
    • Exclusive: Gratuities Included for 2
    • Cruises.com Rewards: Earn more perks on this cruise! Click for details
    • 3rd & 4th Guests Sail Free!
    • 50% Off Cruise Fare + Enhanced More at Sea Perks
     
    Suite from $5,141
    ($467pernight)
    3.8 rating out of 5  (2,498 reviews)
  • Norwegian Jade
    3.9 rating out of 5  (1,411 reviews)

    11 Night Panama Canal: Cartagena & Cozumel

    Norwegian Jade - OPEN BAR!

    Departing from: Tampa, Florida
    Ports of Call:
    • Key West, Florida
    • Cozumel, Mexico
    • George Town, Grand Cayman
    • Ocho Rios, Jamaica
    • Cartagena, Colombia
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • Panama Canal Full Transit
    • Panama City, Panama
    Sailing Dates:
    • January 2025
    interior from
    $921
    $84pernight
    oceanview from
    $1,151
    $105pernight
    balcony from
    $1,821
    $166pernight
    suite from
    $2,221
    $202pernight
    Rewards & Bonus Offers:
    • Exclusive: Gratuities Included for 2
    • Cruises.com Rewards: Earn more perks on this cruise! Click for details
    • Reduced Fares for Third & Fourth Guests
    • 50% Off Cruise Fare + Enhanced More at Sea Perks
    • Call for rates too low to show!
     
    Interior from $921
    ($84pernight)
    3.9 rating out of 5  (1,411 reviews)
  • Emerald Princess
    4 rating out of 5  (1,211 reviews)

    12 Night Panama Canal with Costa Rica & Caribbean

    Emerald Princess

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • Kralendijk, Bonaire
    • Willemstad, Curacao
    • Cartagena, Colombia
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Puerto Limon, Costa Rica
    • George Town, Grand Cayman
    Sailing Dates:
    • February 2025
    interior from
    $1,098
    $92pernight
    oceanview from
    $1,196
    $100pernight
    balcony from
    $2,748
    $229pernight
    suite from
    $3,463
    $289pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards: Earn more perks on this cruise! Click for details
    • Drop & Go Sale: Limited Time Reduced Rates!
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • End of Year Sale: Save Up to 40% + Up to $200 In Savings & More
     
    Interior from $1,098
    ($92pernight)
    4 rating out of 5  (1,211 reviews)
  • Caribbean Princess
    3.9 rating out of 5  (1,897 reviews)

    12 Night Panama Canal with Costa Rica & Caribbean

    Caribbean Princess

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • George Town, Grand Cayman
    • Falmouth, Jamaica
    • Puerto Limon, Costa Rica
    • Panama Canal (Partial Transit)
    • Colon, Panama
    • Oranjestad, Aruba
    • Willemstad, Curacao
    Sailing Dates:
    • November 2025
    • February 2026
    interior from
    $1,389
    $116pernight
    oceanview from
    $1,428
    $119pernight
    balcony from
    $1,989
    $166pernight
    suite from
    $2,399
    $200pernight
    Rewards & Bonus Offers:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Cruises.com Rewards: Earn more perks on this cruise! Click for details
    • Drinks, Tips & Wi-Fi Included with Select Fares
    • End of Year Sale: Save Up to 40% + Up to $200 In Savings & More
     
    Interior from $1,389
    ($116pernight)
    3.9 rating out of 5  (1,897 reviews)
  • Serenade of the Seas
    4.1 rating out of 5  (1,806 reviews)

    16 Night Panama Canal Westward

    Serenade of the Seas

    Departing from: Ft. Lauderdale (Port Everglades), Florida
    Ports of Call:
    • George Town, Grand Cayman
    • Cartagena, Colombia
    • Colon, Panama
    • Panama Canal Full Transit
    • Puerto Quetzal, Guatemala
    • Puerto Vallarta, Mexico
    • Cabo San Lucas, Mexico
    • San Pedro (Los Angeles), California
    Sailing Dates:
    • April 2025
    interior from
    $1,740
    $109pernight
    oceanview from
    $2,121
    $133pernight
    balcony from
    $3,211
    $201pernight
    suite from
    $8,943
    $559pernight
    Rewards & Bonus Offers:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Cruises.com Rewards: Earn more perks on this cruise! Click for details
    • Exclusive Bonus: up to $100 to Spend Onboard
    • 60% Off Second Guest
    • Weekend Flash Sale: $600 Instant Savings
     
    Was $2,514 – Save up to 31%
    Interior from $1,740
    ($109pernight)
    4.1 rating out of 5  (1,806 reviews)
  • Radiance of the Seas
    4.2 rating out of 5  (1,273 reviews)

    15 Night Panama Canal - Westbound

    Radiance of the Seas

    Departing from: Tampa, Florida
    Ports of Call:
    • George Town, Grand Cayman
    • Cartagena, Colombia
    • Colon, Panama
    • Panama Canal Full Transit
    • Puerto Quetzal, Guatemala
    • Puerto Vallarta, Mexico
    • Los Angeles, California
    Sailing Dates:
    • April 2025
    interior from
    $1,607
    $107pernight
    oceanview from
    $1,976
    $132pernight
    balcony from
    $3,039
    $203pernight
    suite from
    Call for availability
    Rewards & Bonus Offers:
    • No Interest or Approval: Book with No Cruise Payment Due Today
    • Cruises.com Rewards: Earn more perks on this cruise! Click for details
    • Exclusive Bonus: up to $100 to Spend Onboard
    • 60% Off Second Guest
    • Weekend Flash Sale: $600 Instant Savings
     
    Was $3,241 – Save up to 50%
    Interior from $1,607
    ($107pernight)
    4.2 rating out of 5  (1,273 reviews)

Discount Panama Canal Cruises

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